Israel Chemical Research Center – IMI TAMI
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The Mini-Pilot Concept

The IMI mini-pilot plant is a 1600 m2, permanent multi-purpose facility for rapid process development on a small scale (up to several kilograms). The mini pilot plant enables reduction of the time required to get new products to the market, by using a scale-down technique that gives full process definition at the 25-50 litre scale.

  1. Scale down of industrial equipment.
  2. Complete process development at small scale.
  3. Controlled and flexible design.
  4. Computer controlled and with ASPEN PLUS, CHETAH and VISIMIX simulators for modeling and optimization.
  5. Batch or continuous operation.
  6. Minimal manpower, raw materials & wastes.
  7. Significant savings in process development costs and time.

The Mini-Pilot Capabilities

  1. Process development based on data supplied by the customer.
  2. Process improvement, verification, de-bottlenecking.
  3. Preparation of samples for market development.

The Mini-Pilot Equipment

  1. 4 fully ventilated enclosed workstations (6m)
  2. Multipurpose glass, glass-lined, stainless steel and Hastelloy C reactors (16-250 litre), all installed in walk-in cupboards.
  3. 4 high pressure bays with autoclaves ranging between 0.5-20 litre up to 100 bar.
  4. RC1 reaction calorimeter – 0.5-2 litre glass or 2 litre stainless steel pressure reactor.
  5. RC-1 reactor equipped with FBRM (Focused Beam Reflectance Measurement) and PVM (Particle Video Microscopy) for study in real time of crystal habit and size during the crystallization process.

Downstream Equipment

  1. Thin/Wiped film evaporators.
  2. Roto-evaporators.
  3. Fractional distillation columns.
  4. Extraction columns.
  5. Filters: centrifuges (basket, peeler), vacuum and pressure filters.
  6. Agitated filter dryer.
  7. Various dryers including spray dryer and paddle dryer.

Membrane Technology Capabilities

  1. Full range of membranes focusing on feasibility tests: micro, ultra, nano, reverse osmosis (RO) and forward osmosis (FO).
  2. Laboratory scale high pressure driven membrane units (dead-end and cross flow) suitable for feasibility tests of a wide spectrum of applications.
  3. Laboratory scale forward osmosis unit suitable for feasibility tests of FO applications.
  4. Process development by combination of various types of membranes.
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