Engineering Services

Process Engineering Services at IMI

Process Engineering Services at IMI 

Process Engineering at IMI is an interdisciplinary effort involving researchers, process engineers and design engineers, supported by a sophisticated simulation capability.

According to the customer's needs, the development procedure within IMI can start with process research in order to discover, test and develop novel chemical reactions or processes. The second stage would then be the process development stage, which confirms the technical, economic and ecological viability of the proposed process.

The process development services include developing complete industrial processes from basic concepts, improving single steps, de-bottlenecking, troubleshooting, and production in ISO 9001, ISO 14001 and ISO 18001 approved facilities and according to customers requirements, with production under cGMP conditions being available.

In addition, IMI provides various engineering solutions for raw materials recycling and waste treatment for specific waste steams and/or for the whole factory streams.

The Integral Method for Process Development, applied in IMI, ensures the most efficient route to a complete process development:

1.   Literature survey

2.   Process and data analysis

3a. Process Safety Analysis, HAZOP, "what-if" scenarios, stability tests.

3b. Generation of data for definition of reaction and down-stream operations with emphasis on process safety:

• Study using RC-1 calorimeter of process thermochemistry. Measurement of heat of reaction, reaction kinetics, detection of eventual potential runaway phenomena.
• Phase equilibrium (vapor pressure, solubility, distribution coefficient)
• Physical constants (density, viscosity, interfacial tension)
• Study of crystalliztion process using FBRM (Focussed Beam Reflectance Measurement) and PVM (Particle Video Microscopy) for the study in real time of crystal habit and size

4. Choice of unit operations

5 Computerized simulation using ASPEN, CHETA, VISIMIX

6. Scale up, process design and choice of equipment. Process flow diagram issued (PFD) for client approval

7. Verification in mini pilot scale of part or all of the process

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